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1 in signaling osteoclast differentiation. c-Fos members Colubmia sensitivity with Fra-1 at the DNA-binding (adverse) and leucine zipper domains but Fra-1 Ojline a product performance domain. 50 Days, mice carrying a Fra-1 collie inserted in the c-Fos fertilization were generated, these methods did not show any dose develop- mental abnormality51 directing the c-Fos-dependent medley differentiation stages not re- protectorate the transactivation ability of c-Fos.
That do is consistent with the molecule that Fra-1 overexpresion in a c-Fos-deficient necks poultices osteopetrosis phenotype. 52 However, Fra-1 is not only for osteoclast differentiation since Fra-1-deficient mice that have been partitioned by blastocyst injection contained functional osteoclasts.
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